This set of courses will discuss the discipline of pharmacology and its integration throughout medical science. Specifically, the content will be organized as follows: 1) Basic Pharmacological Principles; 2) Applied Pharmacology, the concept of applying the basic principles to each organ system with an emphasis on melding pathophysiology with biologic targets for drug therapy; 3) Therapeutics, considered to be the clinical application of applied pharmacology, including the financial implications of therapy, evidence-based medicine, and the limitations of drug therapy and future directions of therapeutics in all disease states, as well as the legal implications of prescription writing; and 4) Advanced Pharmacological Principles, such as cancer therapeutics.